产品货号：
GS4520
中文名称：
重组病毒MIP-2
英文名称：
Recombinant Viral Macrophage Inflammatory Protein-2
产品规格：
10μg
发货周期：
1～3天
产品价格：
询价
分子量：Approximately 8.0kDa,a single,non-glycosylated polypeptide chain containing 70 amino acids.
储存条件：冷冻（-20℃）
概述
Viral MIP-2 is one of the three chemokine-like proteins expressed by the human herpesvirus 8(Kaposis sarcoma-associated herpesvirus,KSHV)and the other is ViMIP-1 and ViMIP-3.It shares 41%and 48%with human MIP-1α and ViMIP-1,respectively.ViMIP-2 has been shown to have antagonist activity towards a wide range of chemokine receptors and has functions of blocking infection by several different human immunodeficiency virus type 1(HIV-1)strains.It may form part of the response to host defenses contributing to virus-induced neoplasia and may have relevance to KSHV and HIV-I interactions.Additionally,ViMIP-2 has been shown to activate and chemoattract human eosinphils.
使用说明
This material is offered by Biorab Biotech for research,laboratory or further evaluation purposes.NOT FOR HUMAN USE.
技术规格
相关搜索：重组病毒MIP-2，MIP-2, Viral
储存条件：冷冻（-20℃）
概述
Viral MIP-2 is one of the three chemokine-like proteins expressed by the human herpesvirus 8(Kaposis sarcoma-associated herpesvirus,KSHV)and the other is ViMIP-1 and ViMIP-3.It shares 41%and 48%with human MIP-1α and ViMIP-1,respectively.ViMIP-2 has been shown to have antagonist activity towards a wide range of chemokine receptors and has functions of blocking infection by several different human immunodeficiency virus type 1(HIV-1)strains.It may form part of the response to host defenses contributing to virus-induced neoplasia and may have relevance to KSHV and HIV-I interactions.Additionally,ViMIP-2 has been shown to activate and chemoattract human eosinphils.
使用说明
This material is offered by Biorab Biotech for research,laboratory or further evaluation purposes.NOT FOR HUMAN USE.
技术规格
| 外观 | Sterile Filtered White lyophilized(freeze-dried)powder. |
| 纯度 | ＞97%by SDS-PAGE and HPLC analyses. |
| 来源 | Escherichia coli. |
| 生物活性 | Fully biologically active when compared to standard.The specific activity is determined by the inhibitory effect on monocyte migration response to human MIP-1 alpha using a concentration range of 1.0μg-10.0μg/ml of viral MIP-2 will inhibit 25ng/ml of human MIP-1 alpha. |
| 成分 | Lyophilized from a 0.2μmfiltered concentrated solution in 20mMPB,pH 7.4,150mM NaCl. |
| 内毒素 | Less than 1 EU/μg of rViMIP-2 as determined by LAL method. |
| 复溶 | We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom.Reconstitute in sterile distilled water or aqueous buffer containing 0.1%BSA to a concentration of 0.1-1.0mg/mL.Stock solutions should be apportioned into working aliquots and stored at ≤ -20?C.Further dilutions should be made in appropriate buffered solutions. |
| 氨基酸序列 | LGASWHRPDK CCLGYQKRPL PQVLLSSWYP TSQLCSKPGV IFLTKRGRQV CADKSKDWVK KLMQQLPVTA |
相关搜索：重组病毒MIP-2，MIP-2, Viral